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Rubicon 抗体 (AA 859-972)

KIAA0226 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F5B5 unconjugated
产品编号 ABIN7193445
发货至: 中国
  • 抗原 See all Rubicon (KIAA0226) 抗体
    Rubicon (KIAA0226) (KIAA0226)
    抗原表位
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 859-972
    适用
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 32
    • 1
    小鼠
    克隆类型
    • 32
    • 1
    单克隆
    标记
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Rubicon antibody is un-conjugated
    应用范围
    • 29
    • 19
    • 14
    • 13
    • 10
    • 9
    • 5
    • 3
    ELISA
    原理
    RUBCN Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. Coli.
    克隆位点
    4F5B5
    亚型
    IgG1
    Top Product
    Discover our top product KIAA0226 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    Rubicon (KIAA0226) (KIAA0226)
    别名
    RUBCN (KIAA0226 产品)
    别名
    RUBICON antibody, 5330403K09 antibody, Kiaa0226 antibody, Rubicon antibody, mKIAA0226 antibody, RUN and cysteine rich domain containing beclin 1 interacting protein antibody, KIAA0226 antibody, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antibody, RUBCN antibody, KIAA0226 antibody, Rubcn antibody
    背景

    Description:

    The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Aliases: SCAR15, RUBICON, KIAA0226

    分子量
    108.6kDa
    基因ID
    9711
    UniProt
    Q92622
    途径
    Autophagy
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