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DFFA 抗体 (AA 179-331)

DFFA 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B10C8 unconjugated
产品编号 ABIN7193432
发货至: 中国
  • 抗原 See all DFFA 抗体
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    抗原表位
    • 15
    • 14
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    AA 179-331
    适用
    • 71
    • 30
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 71
    • 8
    • 1
    小鼠
    克隆类型
    • 73
    • 7
    单克隆
    标记
    • 56
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DFFA antibody is un-conjugated
    应用范围
    • 77
    • 29
    • 15
    • 14
    • 13
    • 13
    • 12
    • 10
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human DFFA (AA: 179-331) expressed in E. coli.
    克隆位点
    2B10C8
    亚型
    IgG1
    Top Product
    Discover our top product DFFA Primary Antibody
  • 应用备注
    WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    别名
    DFFA (DFFA 产品)
    别名
    DFF-45 antibody, DFF1 antibody, ICAD antibody, A330085O09Rik antibody, DFF35 antibody, Dff45 antibody, ICAD-L antibody, ICAD-S antibody, DFFA antibody, zgc:92229 antibody, DNA fragmentation factor subunit alpha antibody, DNA fragmentation factor, alpha subunit antibody, DNA fragmentation factor, 45kDa, alpha polypeptide antibody, DNA fragmentation factor, alpha polypeptide antibody, DFFA antibody, Dffa antibody, dffa antibody
    背景

    Description: Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Aliases: DFF1, ICAD, DFF-45

    分子量
    36.5 kDa
    基因ID
    1676
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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