ATR 抗体 (AA 366-550)
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- 抗原 See all ATR 抗体
- ATR (ATR serine/threonine kinase (ATR))
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抗原表位
- AA 366-550
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATR antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- ATR Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. Coli.
- 克隆位点
- 3G6D2
- 亚型
- IgG1
- Top Product
- Discover our top product ATR Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- ATR (ATR serine/threonine kinase (ATR))
- 别名
- ATR (ATR 产品)
- 别名
- FCTCS antibody, FRP1 antibody, MEC1 antibody, SCKL antibody, SCKL1 antibody, ATR serine/threonine kinase antibody, ataxia telangiectasia and Rad3 related antibody, ATR antibody, Atr antibody
- 背景
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Description:
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1
- 分子量
- 301kDa
- 基因ID
- 545
- UniProt
- Q13535
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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