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ATR 抗体 (AA 366-550)

ATR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G6D2 unconjugated
产品编号 ABIN7193431
发货至: 中国
  • 抗原 See all ATR 抗体
    ATR (ATR serine/threonine kinase (ATR))
    抗原表位
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 366-550
    适用
    • 45
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 4
    • 2
    小鼠
    克隆类型
    • 43
    • 3
    单克隆
    标记
    • 30
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATR antibody is un-conjugated
    应用范围
    • 26
    • 21
    • 20
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    ATR Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. Coli.
    克隆位点
    3G6D2
    亚型
    IgG1
    Top Product
    Discover our top product ATR Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    ATR (ATR serine/threonine kinase (ATR))
    别名
    ATR (ATR 产品)
    别名
    FCTCS antibody, FRP1 antibody, MEC1 antibody, SCKL antibody, SCKL1 antibody, ATR serine/threonine kinase antibody, ataxia telangiectasia and Rad3 related antibody, ATR antibody, Atr antibody
    背景

    Description:

    The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

    Aliases: FRP1, MEC1, SCKL, FCTCS, SCKL1

    分子量
    301kDa
    基因ID
    545
    UniProt
    Q13535
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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