PRNP 抗体 (AA 23-230)
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- 抗原 See all PRNP 抗体
- PRNP (Prion Protein (PRNP))
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抗原表位
- AA 23-230
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRNP antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD230 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD230 (AA: 23-230) expressed in E. Coli.
- 克隆位点
- 3G10G9
- 亚型
- IgG1
- Top Product
- Discover our top product PRNP Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- PRNP (Prion Protein (PRNP))
- 别名
- CD230 (PRNP 产品)
- 背景
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Description:
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Aliases: PRNP, CJD, GSS, PrP, ASCR, KURU, PRIP, PrPc, AltPrP, p27-30, PrP27-30, PrP33-35C
- 分子量
- 27.7kDa
- 基因ID
- 5621
- UniProt
- P04156
- 途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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