XIAP 抗体 (AA 1-268)
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- 抗原 See all XIAP 抗体
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
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抗原表位
- AA 1-268
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This XIAP antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- XIAP Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. Coli.
- 克隆位点
- 4C12G10
- 亚型
- IgG2b
- Top Product
- Discover our top product XIAP Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- 别名
- XIAP (XIAP 产品)
- 别名
- API3 antibody, BIRC4 antibody, IAP-3 antibody, ILP1 antibody, MIHA antibody, XLP2 antibody, hIAP-3 antibody, hIAP3 antibody, api3 antibody, birc4 antibody, ilp1 antibody, miha antibody, xlp2 antibody, xxiap antibody, 1110015C02Rik antibody, Aipa antibody, Api3 antibody, Birc4 antibody, IAP3 antibody, ILP-1 antibody, mXIAP antibody, riap3 antibody, fb73d01 antibody, wu:fb73d01 antibody, zgc:91873 antibody, BIRC8 antibody, X-linked inhibitor of apoptosis antibody, X-linked inhibitor of apoptosis L homeolog antibody, XIAP antibody, xiap antibody, xiap.L antibody, Xiap antibody
- 背景
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Description:
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
Aliases: API3, ILP1, MIHA, XLP2, BIRC4, IAP-3, hIAP3, hIAP-3
- 分子量
- 56.7kDa
- 基因ID
- 331
- UniProt
- P98170
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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