KDM2A 抗体 (AA 1-150)
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- 抗原 See all KDM2A 抗体
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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抗原表位
- AA 1-150
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KDM2A antibody is un-conjugated
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应用范围
- ELISA
- 原理
- KDM2A Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human KDM2A (AA: 1-150) expressed in E. Coli.
- 克隆位点
- 5C11F7
- 亚型
- IgG1
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
- 别名
- KDM2A (KDM2A 产品)
- 背景
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Description:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Aliases: FBL7, CXXC8, FBL11, FBXL11, JHDM1A, LILINA
- 分子量
- 132.8kDa
- 基因ID
- 22992
- UniProt
- Q9Y2K7
- 途径
- Warburg Effect
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