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SETD7 抗体 (AA 107-366)

SETD7 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1B3B8 unconjugated
产品编号 ABIN7193392
发货至: 中国
  • 抗原 See all SETD7 抗体
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    抗原表位
    • 16
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-366
    适用
    • 69
    • 19
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    宿主
    • 60
    • 8
    • 1
    小鼠
    克隆类型
    • 58
    • 10
    • 1
    单克隆
    标记
    • 30
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETD7 antibody is un-conjugated
    应用范围
    • 54
    • 27
    • 22
    • 16
    • 13
    • 13
    • 11
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    SETD7 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human SETD7 (AA: 107-366) expressed in E. Coli.
    克隆位点
    1B3B8
    亚型
    IgG2a
    Top Product
    Discover our top product SETD7 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    别名
    SETD7 (SETD7 产品)
    别名
    KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
    背景

    Description:

    Histone methyltransferase that specifically monomethylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates Lys-189 of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates Lys-372 of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

    Aliases: KMT7, SET7, SET9, SET7/9

    分子量
    40.7kDa
    基因ID
    80854
    UniProt
    Q8WTS6
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