TLR3 抗体 (AA 24-217)
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- 抗原 See all TLR3 抗体
- TLR3 (Toll-Like Receptor 3 (TLR3))
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抗原表位
- AA 24-217
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TLR3 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD283 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD283 (AA: 24-217) expressed in E. Coli.
- 克隆位点
- 6F3G4
- 亚型
- IgG1
- Top Product
- Discover our top product TLR3 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- TLR3 (Toll-Like Receptor 3 (TLR3))
- 别名
- CD283 (TLR3 产品)
- 别名
- CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
- 背景
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Description:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]
Aliases: TLR3 , IIAE2
- 分子量
- 103.8kDa
- 基因ID
- 7098
- UniProt
- O15455
- 途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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