Ataxin 1 抗体 (AA 645-815)
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- 抗原 See all Ataxin 1 (ATXN1) 抗体
- Ataxin 1 (ATXN1)
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抗原表位
- AA 645-815
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ataxin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- ATXN1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human ATXN1 (AA: 645-815) expressed in E. Coli.
- 克隆位点
- 2B8A2
- 亚型
- IgG1
- Top Product
- Discover our top product ATXN1 Primary Antibody
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anti-Ataxin 1 (ATXN1) (AA 645-815) antibody
ATXN1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C7B11 unconjugated
anti-Ataxin 1 (ATXN1) antibodyATXN1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Ataxin 1 (ATXN1) (AA 569-807) antibodyATXN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (C-Term) antibodyATXN1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 331-587) antibodyATXN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 346-475) antibodyATXN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibodyATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 unconjugated
anti-Ataxin 1 (ATXN1) (AA 746-761) antibodyATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibody (FITC)ATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 FITC
anti-Ataxin 1 (ATXN1) (AA 746-761) antibody (Alkaline Phosphatase (AP))ATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 Alkaline Phosphatase (AP)
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- Ataxin 1 (ATXN1)
- 别名
- ATXN1 (ATXN1 产品)
- 背景
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Description:
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 40-83 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). Alternative splicing results in multiple transcript variants, with one variant encoding multiple distinct proteins, ATXN1 and Alt-ATXN1, due to the use of overlapping alternate reading frames.
Aliases: ATX1, SCA1, D6S504E
- 分子量
- 86.9kDa
- 基因ID
- 6310
- UniProt
- P54253
- 途径
- Synaptic Membrane
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