SIGLEC5 抗体 (AA 17-230)
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- 抗原 See all SIGLEC5 抗体
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
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抗原表位
- AA 17-230
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SIGLEC5 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- CD170 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD170 (AA: 17-230) expressed in E. Coli.
- 克隆位点
- 3F5A3
- 亚型
- IgG2a
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
- 别名
- CD170 (SIGLEC5 产品)
- 别名
- CD170 antibody, CD33L2 antibody, OB-BP2 antibody, OBBP2 antibody, SIGLEC-5 antibody, sialic acid binding Ig like lectin 5 antibody, sialic acid-binding Ig-like lectin 5 antibody, sialic acid binding Ig-like lectin 5 antibody, SIGLEC5 antibody, LOC100597560 antibody, Siglec5 antibody
- 背景
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Description:
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Aliases: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5
- 分子量
- 60.7kDa
- 基因ID
- 8778
- UniProt
- O15389
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