CD43 抗体 (AA 20-253)
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- 抗原 See all CD43 (SPN) 抗体
- CD43 (SPN) (Sialophorin (SPN))
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抗原表位
- AA 20-253
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD43 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA
- 原理
- CD43 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD43 (AA: 20-253) expressed in E. Coli.
- 克隆位点
- 1H8B10
- 亚型
- IgG1
- Top Product
- Discover our top product SPN Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- CD43 (SPN) (Sialophorin (SPN))
- 别名
- CD43 (SPN 产品)
- 别名
- CD43 antibody, GALGP antibody, GPL115 antibody, LSN antibody, A630014B01Rik antibody, Cd43 antibody, Galgp antibody, Ly-48 antibody, Ly48 antibody, Lsn antibody, Lsn1 antibody, gpL115 antibody, sialophorin antibody, SPN antibody, Spn antibody
- 背景
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Description:
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.
Aliases: SPN, LSN, GALGP, GPL115
- 分子量
- 40.3kDa
- 基因ID
- 6693
- UniProt
- P16150
- 途径
- Regulation of Leukocyte Mediated Immunity
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