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LRP6 抗体 (AA 1198-1370)

LRP6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A3F5 unconjugated
产品编号 ABIN7193277
发货至: 中国
  • 抗原 See all LRP6 抗体
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    抗原表位
    • 22
    • 21
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1198-1370
    适用
    • 64
    • 46
    • 22
    • 1
    宿主
    • 61
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 63
    • 2
    单克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This LRP6 antibody is un-conjugated
    应用范围
    • 49
    • 26
    • 26
    • 17
    • 16
    • 15
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    LRP6 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human LRP6 (AA: 1198-1370) expressed in E. Coli.
    克隆位点
    1A3F5
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
    别名
    LRP6 (LRP6 产品)
    别名
    lrp6-A antibody, Xlrp6 antibody, adcad2 antibody, lrp6 antibody, LRP6 antibody, ADCAD2 antibody, C030016K15Rik antibody, Cd antibody, Gw antibody, LDL receptor related protein 6 antibody, LDL receptor related protein 6 L homeolog antibody, LDL receptor related protein 6 S homeolog antibody, low density lipoprotein receptor-related protein 6 antibody, low-density lipoprotein receptor-related protein 6 antibody, LRP6 antibody, lrp6.L antibody, lrp6.S antibody, lrp6 antibody, Lrp6 antibody, LOC590395 antibody
    背景

    Description:

    This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

    Aliases: ADCAD2, STHAG7

    分子量
    180kDa
    基因ID
    4040
    UniProt
    O75581
    途径
    WNT signaling, Tube Formation
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