Macrophage Scavenger Receptor 1 抗体 (AA 275-451)
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- 抗原 See all Macrophage Scavenger Receptor 1 (MSR1) 抗体
- Macrophage Scavenger Receptor 1 (MSR1)
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抗原表位
- AA 275-451
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Macrophage Scavenger Receptor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- CD204 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD204 (AA: 275-451) expressed in E. Coli.
- 克隆位点
- 5B8H4
- 亚型
- IgG1
- Top Product
- Discover our top product MSR1 Primary Antibody
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anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 211-320) antibody
MSR1 适用: 人, 小鼠, 绵羊 WB, ELISA, FACS, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (N-Term) antibodyMSR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 271-446) antibodyMSR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 121-220) antibodyMSR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 85-134) antibodyMSR1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 192-451) antibodyMSR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 336-364), (C-Term) antibodyMSR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36746 unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- Macrophage Scavenger Receptor 1 (MSR1)
- 别名
- CD204 (MSR1 产品)
- 别名
- CD204 antibody, SCARA1 antibody, SR-A antibody, SRA antibody, phSR1 antibody, phSR2 antibody, MRS-A antibody, MSR antibody, MSR-A antibody, SR-AI antibody, SR-AII antibody, Scara1 antibody, Scvr antibody, MSR1 antibody, RGD1564316 antibody, macrophage scavenger receptor 1 antibody, scavenger receptor class A member 5 antibody, MSR1 antibody, Msr1 antibody, SCARA5 antibody
- 背景
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Description:
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
Aliases: MSR1, SRA, SR-A, SR-AI, phSR1, phSR2, SCARA1, SR-AII, SR-AIII
- 分子量
- 49.8kDa
- 基因ID
- 4481
- UniProt
- P21757
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