BCL10 抗体 (AA 98-234)
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- 抗原 See all BCL10 抗体
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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抗原表位
- AA 98-234
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BCL10 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- BCL10 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human BCL10 (AA: 98-234) expressed in E. Coli.
- 克隆位点
- 3C11F4
- 亚型
- IgG1
- Top Product
- Discover our top product BCL10 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
- 别名
- BCL10 (BCL10 产品)
- 别名
- CARMEN antibody, CIPER antibody, CLAP antibody, c-E10 antibody, mE10 antibody, BCL10 antibody, AI132454 antibody, BCL-10 antibody, C81403 antibody, ME10 antibody, cE10 antibody, bcl10 antibody, B-cell CLL/lymphoma 10 antibody, B-cell lymphoma/leukemia 10-like antibody, B cell leukemia/lymphoma 10 antibody, B-cell lymphoma/leukemia 10 antibody, BCL10 antibody, Bcl10 antibody, bcl10 antibody, LOC100223183 antibody
- 背景
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Description:
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
Aliases: CLAP, mE10, CIPER, IMD37, c-E10, CARMEN
- 分子量
- 26.3kDa
- 基因ID
- 8915
- UniProt
- O95999
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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