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PD-L1 抗体 (AA 24-153)

PD-L1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 6D9A2 unconjugated
产品编号 ABIN7193243
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    抗原表位
    • 29
    • 16
    • 15
    • 13
    • 11
    • 9
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    AA 24-153
    适用
    • 165
    • 114
    • 62
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    宿主
    • 131
    • 53
    • 19
    • 4
    • 2
    • 1
    小鼠
    克隆类型
    • 113
    • 95
    • 2
    单克隆
    标记
    • 91
    • 15
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    • 11
    • 8
    • 5
    • 4
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    This PD-L1 antibody is un-conjugated
    应用范围
    • 133
    • 102
    • 55
    • 40
    • 35
    • 28
    • 17
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA
    原理
    CD274 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CD274 (AA: 24-153) expressed in E. Coli.
    克隆位点
    6D9A2
    亚型
    IgG2b
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    CD274 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景

    Description:

    This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

    Aliases: B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1

    分子量
    33.3kDa
    基因ID
    29126
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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