CD46 抗体 (AA 35-179)
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- 抗原 See all CD46 抗体
- CD46
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抗原表位
- AA 35-179
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD46 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- 原理
- CD46 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human CD46 (AA: 35-179) expressed in E. Coli.
- 克隆位点
- 1A5A5
- 亚型
- IgG1
- Top Product
- Discover our top product CD46 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- CD46
- 别名
- CD46 (CD46 产品)
- 别名
- AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
- 背景
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Description:
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
Aliases: MCP, TLX, AHUS2, MIC10, TRA2.10
- 分子量
- 43.7kDa
- 基因ID
- 4179
- UniProt
- P15529
- 途径
- Regulation of Actin Filament Polymerization
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