NCKAP1 抗体
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- 抗原 See all NCKAP1 抗体
- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCKAP1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human NCKAP1
- 亚型
- IgG
- Top Product
- Discover our top product NCKAP1 Primary Antibody
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- 应用备注
- ELISA:1:1000-1:2000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NCKAP1 (NCK Associated Protein 1 (NCKAP1))
- 别名
- NCKAP1 (NCKAP1 产品)
- 别名
- HEM2 antibody, NAP1 antibody, NAP125 antibody, p125Nap1 antibody, C79304 antibody, H19 antibody, Hem-2 antibody, Hem2 antibody, Nap1 antibody, mKIAA0587 antibody, mh19 antibody, NCK associated protein 1 antibody, NCK-associated protein 1 antibody, NCK-associated protein 1 L homeolog antibody, NCKAP1 antibody, Nckap1 antibody, nckap1.L antibody
- 背景
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Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.
Aliases: FLJ11291 antibody, KIAA0587 antibody, Membrane associated protein HEM2 antibody, Membrane-associated protein HEM-2 antibody, MGC8981 antibody, NAP 1 antibody, NAP1 antibody, NAP125 antibody, NCK associated protein 1 antibody, NCK associated protein antibody, Nck-associated protein 1 antibody, Nckap1 antibody, NCKP1_HUMAN antibody, OTTHUMP00000163460 antibody, OTTHUMP00000163461 antibody, p125Nap1 antibody
- UniProt
- Q9Y2A7
- 途径
- RTK signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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