GCH1 抗体
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- 抗原 See all GCH1 抗体
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GCH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human GCH1
- 亚型
- IgG
- Top Product
- Discover our top product GCH1 Primary Antibody
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- 应用备注
- ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:5-1:20,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- 别名
- GCH1 (GCH1 产品)
- 别名
- DYT14 antibody, DYT5 antibody, DYT5a antibody, GCH antibody, GTP-CH-1 antibody, GTPCH1 antibody, HPABH4B antibody, GTP-CH antibody, GTPCH antibody, Gch antibody, MGC89622 antibody, gch1a antibody, wu:fc16b10 antibody, zgc:195269 antibody, GTP cyclohydrolase 1 antibody, GTP cyclohydrolase 1-like antibody, GCH1 antibody, Gch1 antibody, gch1 antibody, Weevi_1190 antibody, Halhy_0838 antibody, Sinme_1220 antibody, Sphch_1077 antibody, LOC100136794 antibody
- 背景
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Background: This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Aliases: dystonia 14 antibody, DYT 5 antibody, DYT14 antibody, DYT5 antibody, DYT5a antibody, GCH 1 antibody, GCH antibody, Gch1 antibody, GCH1_HUMAN antibody, GTP CH 1 antibody, GTP CH I antibody, GTP cyclohydrolase 1 (dopa responsive dystonia) antibody, GTP cyclohydrolase 1 antibody, GTP cyclohydrolase I antibody, GTP-CH-I antibody, GTPCH 1 antibody, GTPCH1 antibody, Guanosine 5' triphosphate cyclohydrolase I antibody, HPABH4B antibody
- UniProt
- P30793
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