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CHRDL2 抗体

CHRDL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7190246
发货至: 中国
  • 抗原 See all CHRDL2 抗体
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    适用
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    宿主
    • 28
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    克隆类型
    • 29
    多克隆
    标记
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    This CHRDL2 antibody is un-conjugated
    应用范围
    • 22
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of Human CHRDL2
    亚型
    IgG
    Top Product
    Discover our top product CHRDL2 Primary Antibody
  • 应用备注
    ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    别名
    CHRDL2 (CHRDL2 产品)
    别名
    BNF1 antibody, CHL2 antibody, FKSG37 antibody, 1810022C01Rik antibody, Chl2 antibody, chl antibody, si:dkey-11j5.7 antibody, si:dkey-11j5.7-like antibody, chordin like 2 antibody, chordin-like 2 antibody, CHRDL2 antibody, Chrdl2 antibody, chrdl2 antibody
    背景

    Background: CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.

    Aliases: BNF-1 antibody, BNF1 antibody, Breast tumor novel factor 1 antibody, CHL2 antibody, chordin like 2 antibody, Chordin like protein 2 precursor antibody, Chordin related protein 2 antibody, Chordin-like protein 2 antibody, Chordin-related protein 2 antibody, Chrdl2 antibody, CRDL2_HUMAN antibody, DKFZp586N2124 antibody, FKSG37 antibody

    UniProt
    Q6WN34
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