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AD7C-NTP 抗体

适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7189642
发货至: 中国
  • 抗原 See all AD7C-NTP products
    AD7C-NTP
    适用
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    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
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    This AD7C-NTP antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of Human AD7C-NTP
    亚型
    IgG
  • 应用备注
    ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    AD7C-NTP
    Abstract
    AD7C-NTP 产品
    背景

    Background: The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.

    Aliases: Neuronal thread protein AD7c-NTP

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