ARHGAP24 抗体 (AA 501-600)
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- 抗原 See all ARHGAP24 抗体
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
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抗原表位
- AA 501-600
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGAP24 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 预测反应
- Human,Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ARHGAP24
- 亚型
- IgG
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anti-rho GTPase Activating Protein 24 (ARHGAP24) (AA 1-653) antibody
ARHGAP24 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho GTPase Activating Protein 24 (ARHGAP24) (Internal Region) antibodyARHGAP24 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
- 别名
- ARHGAP24 (ARHGAP24 产品)
- 别名
- FILGAP antibody, RC-GAP72 antibody, RCGAP72 antibody, p73 antibody, p73RhoGAP antibody, 0610025G21Rik antibody, si:ch211-65i12.2 antibody, Rho GTPase activating protein 24 antibody, ARHGAP24 antibody, Arhgap24 antibody, arhgap24 antibody
- 背景
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Synonyms: Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, FilGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP, ARHGAP24, FILGAP
Background: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
- 基因ID
- 83478
- UniProt
- Q8N264
- 途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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