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FGF23 抗体 (AA 21-120)

FGF23 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN714461
发货至: 中国
  • 抗原 See all FGF23 抗体
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    抗原表位
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 58
    • 19
    • 15
    大鼠
    宿主
    • 52
    • 23
    • 2
    克隆类型
    • 56
    • 21
    多克隆
    标记
    • 40
    • 11
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF23 antibody is un-conjugated
    应用范围
    • 41
    • 33
    • 17
    • 11
    • 9
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FGF23
    亚型
    IgG
    Top Product
    Discover our top product FGF23 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Schumacher, Alampour-Rajabi, Ponomariov, Curaj, Wu, Staudt, Rusu, Jankowski, Marx, Jankowski, Brandenburg, Liehn, Schuh: "Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction." in: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, Vol. 40, pp. 47-54, (2019) (PubMed).

    Andersen, Huntley, Sandberg, Heublein, Burnett: "Elevation of circulating but not myocardial FGF23 in human acute decompensated heart failure." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 31, Issue 5, pp. 767-72, (2016) (PubMed).

  • 抗原
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    别名
    FGF23 (FGF23 产品)
    别名
    FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody
    背景

    Synonyms: ADHR, FGFN, HYPF, HPDR2, PHPTC, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, FGF23, UNQ327/PRO9828

    Background: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

    基因ID
    8074
    UniProt
    Q9GZV9
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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