PLG 抗体 (N-Term)
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- 抗原 See all PLG 抗体
- PLG (Plasminogen (PLG))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLG antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from N-terminal of Human PLG.
- 亚型
- IgG
- Top Product
- Discover our top product PLG Primary Antibody
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PLG (Plasminogen (PLG))
- 别名
- PLG (PLG 产品)
- 背景
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Background: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
Petersen T.E., J. Biol. Chem. 265:6104-6111(1990).
Forsgren M., FEBS Lett. 213:254-260(1987).
Browne M.J., Submitted (OCT-1991) to the EMBL/GenBank/DDBJ databases.Aliases: Plasmin antibody, Plasmin heavy chain A antibody, Plasmin light chain B antibody, Plasminogen antibody, PLG antibody, PLMN_HUMAN antibody
- UniProt
- P00747
- 途径
- Complement System, Lipid Metabolism
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