ARHGAP17 抗体
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- 抗原 See all ARHGAP17 抗体
- ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGAP17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from internal of HumanRHG17.
- 亚型
- IgG
- Top Product
- Discover our top product ARHGAP17 Primary Antibody
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))
- 别名
- ARHGAP17 (ARHGAP17 产品)
- 别名
- MST066 antibody, MST110 antibody, MSTP038 antibody, MSTP066 antibody, MSTP110 antibody, NADRIN antibody, PP367 antibody, PP4534 antibody, RICH1 antibody, RICH1B antibody, WBP15 antibody, 5730403H17Rik antibody, Nadrin antibody, Nadrin2 antibody, Rich1 antibody, Wbp15 antibody, Rho GTPase activating protein 17 antibody, ARHGAP17 antibody, arhgap17 antibody, Arhgap17 antibody
- 背景
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Background: Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
Richnau N., J. Biol. Chem. 276:35060-35070(2001).
Ota T., Nat. Genet. 36:40-45(2004).
The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.Aliases: ARHGAP17 antibody, RICH1 antibody, MSTP066 antibody, MSTP110 antibody, Rho GTPase-activating protein 17 antibody, Rho-type GTPase-activating protein 17 antibody, RhoGAP interacting with CIP4 homologs protein 1 antibody, RICH-1 antibody
- UniProt
- Q68EM7
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