TSEN54 抗体
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- 抗原 See all TSEN54 抗体
- TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSEN54 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from internal of Human TSEN54.
- 亚型
- IgG
- Top Product
- Discover our top product TSEN54 Primary Antibody
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))
- 别名
- TSEN54 (TSEN54 产品)
- 别名
- zgc:109927 antibody, 0610034P02Rik antibody, PCH2A antibody, PCH4 antibody, SEN54L antibody, sen54 antibody, tRNA splicing endonuclease subunit 54 antibody, TSEN54 tRNA splicing endonuclease subunit antibody, tRNA splicing endonuclease 54 homolog (S. cerevisiae) antibody, TSEN54 antibody, tsen54 antibody, Tsen54 antibody
- 背景
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Background: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Zody M.C., Nature 440:1045-1049(2006).
Paushkin S.V., Cell 117:311-321(2004).
Ota T., Nat. Genet. 36:40-45(2004).Aliases: HsSen54 antibody, PCH2A antibody, PCH4 antibody, sen54 antibody, SEN54 homolog antibody, SEN54_HUMAN antibody, SEN54L antibody, tRNA-intron endonuclease SEN54 antibody, tRNA-splicing endonuclease subunit SEN54 antibody, Tsen54 antibody, TSEN54 tRNA splicing endonuclease subunit antibody
- UniProt
- Q7Z6J9
- 途径
- Synaptic Membrane
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