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- 抗原 See all CCAR2 抗体
- CCAR2 (Cell Cycle and Apoptosis Regulator 2 (CCAR2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCAR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from internal of Human KIAA1967.
- 亚型
- IgG
- Top Product
- Discover our top product CCAR2 Primary Antibody
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anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) antibody
CCAR2 适用: 人, 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) (AA 1-923) antibodyCCAR2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) (AA 1-923) antibodyCCAR2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) (AA 654-923) antibodyCCAR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) (AA 5-365) antibodyCCAR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E6 unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) antibodyCCAR2 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) (Internal Region) antibodyCCAR2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle and Apoptosis Regulator 2 (CCAR2) (AA 842-855) antibodyVerified CCAR2 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CCAR2 (Cell Cycle and Apoptosis Regulator 2 (CCAR2))
- 别名
- CCAR2 (CCAR2 产品)
- 别名
- DBC-1 antibody, DBC1 antibody, KIAA1967 antibody, NET35 antibody, p30 DBC antibody, p30DBC antibody, 2610301G19Rik antibody, mKIAA1967 antibody, RGD1309922 antibody, Kiaa1967 antibody, cell cycle and apoptosis regulator 2 antibody, cell cycle activator and apoptosis regulator 2 antibody, CCAR2 antibody, Ccar2 antibody
- 背景
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Background: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress.
Nagase T., DNA Res. 8:319-327(2001).
Hamaguchi M., Proc. Natl. Acad. Sci. U.S.A. 99:13647-13652(2002).
Olsen J.V., Cell 127:635-648(2006).Aliases: CCAR2 antibody, DBC1 antibody, KIAA1967Cell cycle and apoptosis regulator protein 2 antibody, Cell division cycle and apoptosis regulator protein 2 antibody, DBIRD complex subunit KIAA1967 antibody, Deleted in breast cancer gene 1 protein antibody, DBC-1 antibody, DBC.1 antibody, NET35 antibody, p30 DBC antibody
- UniProt
- Q8N163
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