CIT 抗体
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- 抗原 See all CIT 抗体
- CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CIT antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from internal of Human CTRO.
- 亚型
- IgG
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- 应用备注
- IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))
- 别名
- CIT (CIT 产品)
- 别名
- CIT antibody, crik antibody, xcit antibody, stk21 antibody, C030025P15Rik antibody, CRIK antibody, CRIK-SK antibody, Cit-k antibody, STK21 antibody, citron rho-interacting serine/threonine kinase antibody, citron (rho-interacting, serine/threonine kinase 21) antibody, citron Rho-interacting kinase antibody, citron antibody, Cit antibody, CIT antibody, LOC100083347 antibody, cit antibody
- 背景
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Background: Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Nagase T., DNA Res. 6:63-70(1999).
Scherer S.E., Nature 440:346-351(2006).
Gruneberg U., J. Cell Biol. 172:363-372(2006).Aliases: CIT antibody, CRIK antibody, KIAA0949 antibody, STK21Citron Rho-interacting kinase antibody, CRIK antibody, EC 2.7.11.1 antibody, Serine/threonine-protein kinase 21 antibody
- UniProt
- O14578
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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