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ACVR1C/ALK7 抗体

ACVR1C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7183057
发货至: 中国
  • 抗原 See all ACVR1C/ALK7 (ACVR1C) 抗体
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    适用
    • 43
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    宿主
    • 52
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    克隆类型
    • 54
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    多克隆
    标记
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    This ACVR1C/ALK7 antibody is un-conjugated
    应用范围
    • 50
    • 24
    • 19
    • 13
    • 13
    • 10
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    • 3
    • 2
    • 1
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    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from internal of Human ACTR-1C.
    亚型
    IgG
    Top Product
    Discover our top product ACVR1C Primary Antibody
  • 应用备注
    IHC:1:50-1:100, IF:1:100-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    别名
    ACVR1C (ACVR1C 产品)
    别名
    ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
    背景

    Background: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

    Bondestam J., Cytogenet. Cell Genet. 95:157-162(2001).
    Roberts H.J., Biol. Reprod. 68:1719-1726(2003).
    Hillier L.W., Nature 434:724-731(2005).

    Aliases: Activin A receptor, type IC antibody, Activin receptor like kinase 7 antibody, Activin receptor type 1C precursor antibody, Activin receptor type IC antibody, Activin receptor type-1C antibody, Activin receptor-like kinase 7 antibody, ACTR IC antibody, ACTR-IC antibody, ACTRIC antibody, ACV1C_HUMAN antibody, Acvr1c antibody, ACVRLK7 antibody, ALK 7 antibody, ALK-7 antibody, ALK7 antibody

    UniProt
    Q8NER5
    途径
    Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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