Neuregulin 1 抗体 (Isoform 10)
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- 抗原 See all Neuregulin 1 (NRG1) 抗体
- Neuregulin 1 (NRG1)
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抗原表位
- Isoform 10
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neuregulin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from Human NRG1 isoform-10.
- 亚型
- IgG
- Top Product
- Discover our top product NRG1 Primary Antibody
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Neuregulin 1 (NRG1)
- 别名
- NRG1 (NRG1 产品)
- 别名
- 6030402G23Rik antibody, ARIA antibody, D230005F13Rik antibody, GGF antibody, GGFII antibody, HRG antibody, HRGalpha antibody, Hgl antibody, NDF antibody, SMDF antibody, GGF2 antibody, HGL antibody, HRG1 antibody, HRGA antibody, MST131 antibody, NRG-1 antibody, heregulin antibody, nrg1-A antibody, pro-neuregulin-1 antibody, NRG1 antibody, wu:fm70e01 antibody, DKFZp459A1838 antibody, neuregulin 1 antibody, histidine rich glycoprotein antibody, neuregulin 1 L homeolog antibody, Nrg1 antibody, NRG1 antibody, HRG antibody, nrg1.L antibody, nrg1 antibody
- 背景
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Background: The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).
Xiao-Feng Le, Cancer Res., Jul 2000, 60: 3522 - 3531.
Samuel D. H. Chan, J. Biol. Chem., Sep 1995, 270: 22608.
Daniel C. Gamett, J. Biol. Chem., Aug 1995, 270: 19022.
Mohammed Rahmatullah, Mol. Cell. Biol., Nov 1998, 18: 6245 - 6252.Aliases: Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, NRG1, GGF
- UniProt
- Q15491
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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