WTAP 抗体 (C-Term)
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- 抗原 See all WTAP 抗体
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WTAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from C-terminal of Human WTAP.
- 亚型
- IgG
- Top Product
- Discover our top product WTAP Primary Antibody
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- WTAP (Wilms Tumor 1 Associated Protein (WTAP))
- 别名
- WTAP (WTAP 产品)
- 别名
- MGC75954 antibody, WTAP antibody, RGD1563824 antibody, wu:fi29a09 antibody, zgc:66202 antibody, 2810408K05Rik antibody, 9430038B09Rik antibody, WT1 associated protein antibody, Wilms tumor 1 associated protein antibody, wilms tumor 1 associated protein antibody, WT1 associated protein L homeolog antibody, Wilms tumour 1-associating protein antibody, wtap antibody, WTAP antibody, CpipJ_CPIJ006489 antibody, Wtap antibody, wtap.L antibody
- 背景
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Background: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes.
Ortega A., J. Biol. Chem. 278:3040-3047(2003).
Nagase T., DNA Res. 2:37-43(1995).
Mungall A.J., Nature 425:805-811(2003).Aliases: DKFZp686F20131 antibody, Female-lethal(2)D homolog antibody, FL2D_HUMAN antibody, hFL(2)D antibody, KIAA0105 antibody, MGC3925 antibody, Mum2 antibody, OTTHUMP00000017522 antibody, OTTHUMP00000017523 antibody, PNAS 132 antibody, PNAS-132 antibody, PNAS132 antibody, Pre mRNA splicing regulator WTAP antibody, Pre-mRNA-splicing regulator WTAP antibody, Putative pre mRNA splicing regulator female lethal 2D homolog antibody, Putative pre mRNA splicing regulator female lethal(2D) antibody, Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody, putative pre-mRNA splicing regulator female-lethal(2D) antibody, Wilms tumor 1 associated protein antibody, Wilms tumor 1 associating protein antibody, Wilms tumor 1-associating protein antibody, Wilms' tumor 1 associating protein antibody, Wilms' tumour 1-associating protein antibody, WT1 associated protein antibody, WT1-associated protein antibody, WT1-associating protein antibody, wtap antibody
- UniProt
- Q15007
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