电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NDFIP1 抗体 (C-Term)

NDFIP1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7180214
发货至: 中国
  • 抗原 See all NDFIP1 抗体
    NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    C-Term
    适用
    • 40
    • 15
    • 11
    宿主
    • 38
    • 2
    • 1
    • 1
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 16
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDFIP1 antibody is un-conjugated
    应用范围
    • 24
    • 24
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from C-terminal of Human NDFIP1.
    亚型
    IgG
    Top Product
    Discover our top product NDFIP1 Primary Antibody
  • 应用备注
    WB:1:500-1:3000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
    别名
    NDFIP1 (NDFIP1 产品)
    别名
    zgc:55546 antibody, wu:fc17e11 antibody, n4wbp5 antibody, MGC108163 antibody, ndfip1 antibody, NDFIP1 antibody, N4WBP5 antibody, 0610010M22Rik antibody, N4wbp5 antibody, Nedd4 family interacting protein 1 antibody, Nedd4 WW domain-binding protein 5 antibody, ndfip1 antibody, NDFIP1 antibody, n4wbp5 antibody, Ndfip1 antibody
    背景

    Background: Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation By similarity. In cortical neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably through PTEN destabilization and on MAPK8 through ITCH-dependent MAP2K4 inactivation. As a result, may control cell growth rate.

    Petroziello J.M., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
    Matsuda A., Oncogene 22:3307-3318(2003).
    Otsuki T., DNA Res. 12:117-126(2005).

    Aliases: 0610010M22Rik antibody, Breast cancer associated protein SGA 1M antibody, Breast cancer-associated protein SGA-1M antibody, MGC10924 antibody, N4WBP5 antibody, Ndfip1 antibody, Nedd4 family interacting protein 1 antibody, NEDD4 family-interacting protein 1 antibody, NEDD4 WW domain binding protein 5 antibody, NEDD4 WW domain-binding protein 5 antibody, NFIP1_HUMAN antibody, Putative MAPK activating protein PM13 antibody, Putative MAPK-activating protein PM13 antibody, Putative NF kappa B activating protein 164 antibody, Putative NF-kappa-B-activating protein 164 antibody, Putative NFKB and MAPK activating protein antibody, Putative NFKB and MAPK-activating protein antibody

    UniProt
    Q9BT67
    途径
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity
You are here:
客服