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- 抗原 See all NDFIP1 抗体
- NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NDFIP1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from C-terminal of Human NDFIP1.
- 亚型
- IgG
- Top Product
- Discover our top product NDFIP1 Primary Antibody
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anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 2-116) antibody
NDFIP1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (C-Term) antibodyNDFIP1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 1-221) antibodyNDFIP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 1-116) antibodyNDFIP1 适用: 人 EIA, RIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
- 别名
- NDFIP1 (NDFIP1 产品)
- 别名
- zgc:55546 antibody, wu:fc17e11 antibody, n4wbp5 antibody, MGC108163 antibody, ndfip1 antibody, NDFIP1 antibody, N4WBP5 antibody, 0610010M22Rik antibody, N4wbp5 antibody, Nedd4 family interacting protein 1 antibody, Nedd4 WW domain-binding protein 5 antibody, ndfip1 antibody, NDFIP1 antibody, n4wbp5 antibody, Ndfip1 antibody
- 背景
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Background: Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation By similarity. In cortical neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably through PTEN destabilization and on MAPK8 through ITCH-dependent MAP2K4 inactivation. As a result, may control cell growth rate.
Petroziello J.M., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Matsuda A., Oncogene 22:3307-3318(2003).
Otsuki T., DNA Res. 12:117-126(2005).Aliases: 0610010M22Rik antibody, Breast cancer associated protein SGA 1M antibody, Breast cancer-associated protein SGA-1M antibody, MGC10924 antibody, N4WBP5 antibody, Ndfip1 antibody, Nedd4 family interacting protein 1 antibody, NEDD4 family-interacting protein 1 antibody, NEDD4 WW domain binding protein 5 antibody, NEDD4 WW domain-binding protein 5 antibody, NFIP1_HUMAN antibody, Putative MAPK activating protein PM13 antibody, Putative MAPK-activating protein PM13 antibody, Putative NF kappa B activating protein 164 antibody, Putative NF-kappa-B-activating protein 164 antibody, Putative NFKB and MAPK activating protein antibody, Putative NFKB and MAPK-activating protein antibody
- UniProt
- Q9BT67
- 途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity
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