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- 抗原 See all MBTPS1 抗体
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBTPS1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from C-terminal of Human MBTPS1.
- 亚型
- IgG
- Top Product
- Discover our top product MBTPS1 Primary Antibody
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anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) antibody
MBTPS1 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (Internal Region) antibodyMBTPS1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 17-70) antibodyMBTPS1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 803-1052) antibodyMBTPS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 246-355) antibodyMBTPS1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) antibodyMBTPS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 187-400) antibodyMBTPS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 187-400) antibodyMBTPS1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1) (AA 803-1052) antibodyMBTPS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MBTPS1 (Membrane-Bound Transcription Factor Peptidase, Site 1 (MBTPS1))
- 别名
- MBTPS1 (MBTPS1 产品)
- 别名
- PCSK8 antibody, S1P antibody, SKI-1 antibody, 0610038M03Rik antibody, AV003995 antibody, Ski1 antibody, mKIAA0091 antibody, S1p antibody, Ski-1 antibody, membrane bound transcription factor peptidase, site 1 antibody, membrane-bound transcription factor peptidase, site 1 antibody, MBTPS1 antibody, Mbtps1 antibody
- 背景
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Background: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.
Nakajima T., J. Hum. Genet. 45:212-217(2000).
Nagase T., DNA Res. 2:37-43(1995).
Bechtel S., BMC Genomics 8:399-399(2007).Aliases: MBTPS1 antibody, KIAA0091 antibody, S1P antibody, SKI1Membrane-bound transcription factor site-1 protease antibody, EC 3.4.21.112 antibody, Endopeptidase S1P antibody, Subtilisin/kexin-isozyme 1 antibody, SKI-1 antibody
- UniProt
- Q14703
- 途径
- ER-Nucleus Signaling
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