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- 抗原 See all TK1 抗体
- TK1 (Thymidine Kinase 1, Soluble (TK1))
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抗原表位
- Ser13
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human TK around the phosphorylation site of serine 13 (P-G-S(p)-P-S).
- 亚型
- IgG
- Top Product
- Discover our top product TK1 Primary Antibody
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anti-Thymidine Kinase 1, Soluble (TK1) (AA 1-234) antibody
TK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 2-234) antibodyTK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (N-Term) antibodyTK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 139-173) antibodyTK1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB56912 unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 1-234) antibodyTK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 1-50) antibodyTK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 2-234) antibodyTK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 1-234) antibodyTK1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (AA 2-234) antibodyTK1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Thymidine Kinase 1, Soluble (TK1) (N-Term) antibodyTK1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TK1 (Thymidine Kinase 1, Soluble (TK1))
- 别名
- TK1 (TK1 产品)
- 别名
- fi19b06 antibody, zgc:55362 antibody, wu:fi19b06 antibody, TK1 antibody, tk2 antibody, D530002A18Rik antibody, Tk-1 antibody, Tk1a antibody, Tk1b antibody, TK2 antibody, Tk antibody, TK antibody, thymidine kinase 1, soluble antibody, thymidine kinase 1 antibody, thymidine kinase, cytosolic antibody, Thymidine kinase, cytosolic antibody, temporal expression: early antibody, thymidine kinase antibody, Tk thymidine kinase antibody, tk1 antibody, TK1 antibody, EDI_049980 antibody, kith antibody, J2R antibody, HVT031 antibody, Tk1 antibody, tk antibody
- 背景
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Background: Thymidine kinases play a critical role in generating the DNA synthetic precursor deoxythymidine triphosphate (dTTP) by catalyzing the phosphotransfer of phosphate from ATP to deoxythymidine (dT) and thymidine (T) in the cell.TK1 expression and activity is regulated in a cell cycle-dependent manner, accumulating during G1-phase to peak levels in S-phase before being degraded prior to cell division. Stability, but not activity, may be regulated via phosphorylation of TK1 at Ser13 by Cdc2 and/or Cdk2, but the precise mode of regulation remains elusive. These observations indicate that TK1 might be a useful marker of cell proliferation, however, recent studies have shown that TK1 plays a more significant role in the DNA damage response.
N Singh, Mol. Cell. Biol., May 1991, 11: 2362 - 2374.
Bin Tian, Am. J. Pathol., Aug 2003, 163: 789.
RenGerolami, Cancer Res., Feb 2000, 60: 993 - 1001.
Catia Traversari, Blood, Jun 2007, 109: 4708 - 4715Aliases: cytosolic antibody, KITH_HUMAN antibody, Thymidine kinase 1 antibody, Thymidine kinase 1 soluble antibody, Thymidine kinase 1 soluble isoform antibody, Thymidine kinase antibody, Thymidine kinase cytosolic antibody, TK 1 antibody, TK 2 antibody, TK1 antibody, Tk1a antibody, Tk1b antibody, TK2 antibody
- UniProt
- P04183
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