MEF2C 抗体 (Ser396)
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- 抗原 See all MEF2C 抗体
- MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
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抗原表位
- Ser396
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEF2C antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human MEF2C around the phosphorylation site of serine 396 (P-V-S(p)-P-P).
- 亚型
- IgG
- Top Product
- Discover our top product MEF2C Primary Antibody
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
- 别名
- MEF2C (MEF2C 产品)
- 别名
- MEF2C antibody, XMEF2C antibody, si:ch211-202e12.2 antibody, C5DELq14.3 antibody, DEL5q14.3 antibody, 5430401D19Rik antibody, 9930028G15Rik antibody, AV011172 antibody, Mef2 antibody, RGD1563119 antibody, id:ibd5026 antibody, mef2c antibody, wu:fc05b06 antibody, zgc:64184 antibody, zgc:85726 antibody, myocyte enhancer factor 2C antibody, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) antibody, myocyte enhancer factor 2cb antibody, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) L homeolog antibody, myocyte enhancer factor 2ca antibody, MEF2C antibody, mef2c antibody, mef2cb antibody, mef2c.L antibody, Mef2c antibody, mef2ca antibody
- 背景
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Background: Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture By similarity. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550(1993).
McDermott J.C., Mol. Cell. Biol. 13:2564-2577(1993).
Wang A.H., Mol. Cell. Biol. 19:7816-7827(1999).Aliases: C5DELq14.3 antibody, DEL5q14.3 antibody, MADS box transcription enhancer factor 2 polypeptide C (myocyte enhancer factor 2C) antibody, MADS box transcription enhancer factor 2, polypeptide C antibody, MEF2C antibody, MEF2C_HUMAN antibody, Myocyte enhancer factor 2C antibody, Myocyte specific enhancer factor 2C antibody, Myocyte-specific enhancer factor 2C antibody, OTTHUMP00000222409 antibody, Similar to MADS box transcription enhancer factor 2 polypeptide C antibody
- UniProt
- Q06413
- 途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
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