CBX5 抗体 (Ser92)
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- 抗原 See all CBX5 抗体
- CBX5 (Chromobox Homolog 5 (CBX5))
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抗原表位
- Ser92
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human HP1 alpha around the phosphorylation site of serine 92 (R-K-S(p)-N-F).
- 亚型
- IgG
- Top Product
- Discover our top product CBX5 Primary Antibody
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- 应用备注
- WB:1:500-1:3000, IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CBX5 (Chromobox Homolog 5 (CBX5))
- 别名
- CBX5 (CBX5 产品)
- 背景
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Background: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Saunders W.S., J. Cell Sci. 104:573-582(1993).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ye Q., J. Biol. Chem. 271:14653-14656(1996).Aliases: Antigen p25 antibody, CBX5 antibody, CBX5_HUMAN antibody, CG8409 antibody, Chromobox 5 antibody, Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, Chromobox homolog 5 antibody, Chromobox protein homolog 5 antibody, Epididymis luminal protein 25 antibody, HEL25 antibody, Heterochromatin protein 1 alpha antibody, Heterochromatin protein 1 antibody, Heterochromatin protein 1 homolog alpha antibody, HP1 alpha antibody, HP1 alpha homolog antibody, HP1 antibody, HP1A antibody, HP1Hs alpha antibody, Su(var)205 antibody
- UniProt
- P45973
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