HDAC7 抗体 (Ser155)
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- 抗原 See all HDAC7 抗体
- HDAC7 (Histone Deacetylase 7 (HDAC7))
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抗原表位
- Ser155
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HDAC7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human HDAC7A around the phosphorylation site of serine 155 (T-V-S(p)-E-P).
- 亚型
- IgG
- Top Product
- Discover our top product HDAC7 Primary Antibody
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HDAC7 (Histone Deacetylase 7 (HDAC7))
- 别名
- HDAC7 (HDAC7 产品)
- 别名
- HD7A antibody, HDAC7A antibody, 5830434K02Rik antibody, HD7 antibody, HD7a antibody, Hdac7a antibody, mFLJ00062 antibody, hdac7a antibody, K2K18.5 antibody, K2K18_5 antibody, histone deacetylase7 antibody, histone deacetylase 7 antibody, histone deacetylase7 antibody, HDAC7 antibody, Hdac7 antibody, hdac7 antibody, HDA7 antibody
- 背景
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Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors By similarity. May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.
Walsh M.J., Submitted (FEB-2000).
Zelent A., Submitted (MAY-2003).
Sugano S., Nat. Genet. 36:40-45(2004).Aliases: DKFZP586J0917 antibody, FLJ99588 antibody, HD 7a antibody, HD7 antibody, HD7a antibody, HDAC 7 antibody, HDAC 7A antibody, Hdac7 antibody, HDAC7_HUMAN antibody, HDAC7A antibody, Histone deacetylase 7 antibody, Histone deacetylase 7A antibody, OTTHUMP00000202813 antibody, OTTHUMP00000202814 antibody
- UniProt
- Q8WUI4
- 途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
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