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GAB2 抗体 (Ser159)

GAB2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7180017
发货至: 中国
  • 抗原 See all GAB2 抗体
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    抗原表位
    • 24
    • 21
    • 16
    • 11
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser159
    适用
    • 122
    • 91
    • 85
    • 3
    • 3
    • 3
    • 3
    宿主
    • 121
    • 1
    • 1
    克隆类型
    • 123
    多克隆
    标记
    • 39
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This GAB2 antibody is un-conjugated
    应用范围
    • 85
    • 39
    • 39
    • 39
    • 19
    • 14
    • 13
    • 9
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized non-phosphopeptide derived from Human GRB2 around the phosphorylation site of serine 159 (K-S-S(p)-A-P).
    亚型
    IgG
    Top Product
    Discover our top product GAB2 Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    别名
    GAB2 (GAB2 产品)
    别名
    GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
    背景

    Background: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

    Nishida K., Blood 93:1809-1816(1999).
    Nagase T., DNA Res. 5:31-39(1998).
    Taylor T.D., Nature 440:497-500(2006).

    Aliases: GAB 2 antibody, Gab2 antibody, GAB2_HUMAN antibody, Grb 2 associated binder 2 antibody, GRB 2 associated binding protein 2 antibody, Grb2 associated binder 2 antibody, GRB2 associated binder 2 pp100 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binder 2 antibody, GRB2-associated-binding protein 2 antibody, Growth factor receptor bound protein 2 associated protein 2 antibody, Growth factor receptor bound protein 2-associated protein 2 antibody, KIAA0571 antibody, p97 antibody, PH domain containing adaptor molecule p97 antibody, pp100 antibody

    UniProt
    Q9UQC2
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
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