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- 抗原 See all DDR1 抗体
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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抗原表位
- Tyr796
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized non-phosphopeptide derived from Human DDR1 around the phosphorylation site of tyrosine 796.
- 亚型
- IgG
- Top Product
- Discover our top product DDR1 Primary Antibody
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anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 568-829) antibodyDDR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-176) antibodyDDR1 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4F2C12 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibodyDDR1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB14442 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47), (N-Term) antibodyDDR1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01477 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47) antibodyDDR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-120) antibodyDDR1 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 396-430) antibodyDDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-876) antibodyDDR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (Internal Region) antibodyDDR1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
- 别名
- DDR1 (DDR1 产品)
- 别名
- CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody
- 背景
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Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing By similarity. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
di Marco E., J. Biol. Chem. 268:24290-24295(1993).
Johnson J.D., Proc. Natl. Acad. Sci. U.S.A. 90:5677-5681(1993).Aliases: CAK antibody, CD 167 antibody, CD167 antibody, CD167 antigen-like family member A antibody, CD167a antibody, Cell adhesion kinase antibody, DDR 1 antibody, DDR antibody, DDR1 antibody, DDR1_HUMAN antibody, Discoidin domain receptor antibody, Discoidin domain receptor tyrosine kinase 1 antibody, Discoidin receptor tyrosine kinase antibody, Discoidin receptor tyrosine kinase isoform a antibody, EDDR 1 antibody, EDDR1 antibody, Epithelial discoidin domain receptor 1 antibody, Epithelial discoidin domain-containing receptor 1 antibody, Epithelial specific receptor kinase antibody, HGK2 antibody, Mammarian carcinoma kinase 10 antibody, Mammary carcinoma kinase 10 antibody, MCK-10 antibody, MCK10 antibody, NEP antibody, Neuroepithelial tyrosine kinase antibody, Neurotrophic tyrosine kinase receptor type 4 antibody, NTRK 4 antibody, NTRK4 antibody, OTTHUMP00000029343 antibody, OTTHUMP00000029344 antibody, OTTHUMP00000029345 antibody, OTTHUMP00000029346 antibody, OTTHUMP00000029347 antibody, OTTHUMP00000164863 antibody, OTTHUMP00000164867 antibody, OTTHUMP00000222080 antibody, Protein-tyrosine kinase 3A antibody, Protein-tyrosine kinase RTK-6 antibody, PTK 3 antibody, PTK 3A protein tyrosine kinase 3A antibody, PTK3 antibody, PTK3A antibody, Receptor tyrosine kinase NEP antibody, RTK 6 antibody, RTK6 antibody, TRK E antibody, TRKE antibody, Tyrosine kinase DDR antibody, Tyrosine kinase receptor E antibody, Tyrosine-protein kinase CAK antibody
- UniProt
- Q08345
- 途径
- RTK signaling, Smooth Muscle Cell Migration
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