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eIF4EBP1 抗体 (Ser65)

EIF4EBP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7179965
发货至: 中国
  • 抗原 See all eIF4EBP1 (EIF4EBP1) 抗体
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    抗原表位
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    Ser65
    适用
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    宿主
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    克隆类型
    • 212
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    多克隆
    标记
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    This eIF4EBP1 antibody is un-conjugated
    应用范围
    • 197
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized non-phosphopeptide derived from Human 4E-BP1 around the phosphorylation site of serine 65 (R-N-S(p)-P-V).
    亚型
    IgG
    Top Product
    Discover our top product EIF4EBP1 Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    别名
    EIF4EBP1 (EIF4EBP1 产品)
    背景

    Background: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

    Anne-Claude Gingras, Genes & Dev., Jun 1999, 13: 1422.
    Guangming Liu, J. Biol. Chem., Mar 2002, 277: 8810 - 8816.
    Ya-Ping Jiang, J. Biol. Chem., Mar 2001, 276: 10943 - 10951.

    Aliases: 4E-BP1 antibody, 4EBP1 antibody, 4EBP1_HUMAN antibody, BP 1 antibody, eIF4E binding protein 1 antibody, eIF4E-binding protein 1 antibody, Eif4ebp1 antibody, Eukaryotic translation initiation factor 4E-binding protein 1 antibody, PHAS-I antibody, PHASI antibody, Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody

    UniProt
    Q13541
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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