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- 抗原 See all SOCS3 抗体
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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抗原表位
- AA 1-225
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOCS3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Rat Suppressor of cytokine signaling 3 protein (1-225AA)
- 亚型
- IgG
- Top Product
- Discover our top product SOCS3 Primary Antibody
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anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody
SOCS3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 155-225) antibodySOCS3 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-224) antibodySOCS3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-226) antibodySOCS3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) antibodySOCS3 适用: 人 WB 宿主: 小鼠 Monoclonal SO1 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 71-85), (Middle Region) antibodySOCS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- 别名
- Socs3 (SOCS3 产品)
- 背景
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Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST (By similarity).
Aliases: Socs3 antibody, Cish3Suppressor of cytokine signaling 3 antibody, SOCS-3 antibody, Cytokine-inducible SH2 protein 3 antibody
- UniProt
- O88583
- 途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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