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IL-7 抗体

IL7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7178671
发货至: 中国
  • 抗原 See all IL-7 (IL7) 抗体
    IL-7 (IL7) (Interleukin 7 (IL7))
    适用
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    宿主
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    克隆类型
    • 70
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    多克隆
    标记
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    This IL-7 antibody is un-conjugated
    应用范围
    • 74
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of Human IL7
    亚型
    IgG
    Top Product
    Discover our top product IL7 Primary Antibody
  • 应用备注
    WB:1:500-1:2000, IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IL-7 (IL7) (Interleukin 7 (IL7))
    别名
    IL7 (IL7 产品)
    别名
    IL7 antibody, IL-7 antibody, A630026I06Rik antibody, Il-7 antibody, hlb368 antibody, interleukin 7 antibody, IL7 antibody, Il7 antibody
    背景

    Background: IL-7 plays a key role in lymphopoiesis and lymphoid homeostasis. Stromal and epithelial cells within the bone marrow and thymus produce IL-7. The primary targets of IL-7 are T cells, B cells, and dendritic cells. IL-7 is crucial for T cell development, the importance of which is underscored by the lack of T cells in both mice and humans that are deficient in IL-7/IL-7R signaling. While IL-7 appears to be required for B cell development in mice, the role of IL-7 in human B cell development is unclear. In addition to its effects on T cell lymphopoiesis, IL-7 promotes the maintenance and survival of naïve and memory αβ T cells, as well as γδ T cells. The IL-7 receptor is a heterodimer of the common γ chain, γc, and the IL-7-specific IL-7Rα. IL-7 activates PI3K/Akt, Jak1/2, and Stat1, 3, and 5.

    Aliases: IL 7 antibody; IL-7 antibody; Il7 antibody; IL7_HUMAN antibody; Interleukin 7 antibody; Interleukin-7 antibody; LP-1 antibody; Lymphopoietin 1 antibody

    UniProt
    P13232
    途径
    JAK/STAT Signaling
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