IL-13 抗体
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- 抗原 See all IL-13 (IL13) 抗体
- IL-13 (IL13) (Interleukin 13 (IL13))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-13 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of Human IL13
- 亚型
- IgG
- Top Product
- Discover our top product IL13 Primary Antibody
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- 应用备注
- WB:1:500-1:2000, IHC:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- IL-13 (IL13) (Interleukin 13 (IL13))
- 别名
- IL13 (IL13 产品)
- 别名
- IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
- 背景
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Background: IL-13 is produced by T cells and is important in the TH2 response. IL-13 targets include B cells, eosinophils, fibroblasts, mast cells and macrophages. IL-13 binds specifically to IL-13Rα1 that complexes with IL-4Rα to form the Type II IL-4R. Jak1 and Tyk2 are activated and signal through Stat3 and Stat6. IL-13Rα2 is a different gene product, lacks the intracellular domain, does not complex with IL-4Rα and does not signal. The extracellular domain of IL-13Rα2 is often elevated in diseased states. IL-13 plays key roles in airway hyperresponsiveness (AHR) of allergic asthma and modulates resistance to parasitic organisms.
Aliases: Allergic rhinitis antibody, ALRH antibody, BHR 1 antibody, BHR1 antibody, Bronchial hyperresponsiveness 1 (bronchial asthma) antibody, IL 13 antibody, IL-13 antibody, Il13 antibody, IL13_HUMAN antibody, Interleukin 13 antibody, Interleukin-13 antibody, interleukin13 antibody, MGC116786 antibody, MGC116788 antibody, MGC116789 antibody, NC 30 antibody, NC30 antibody, P 600 antibody, P600 antibody
- UniProt
- P35225
- 途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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