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CTCFL 抗体 (AA 1-636)

CTCFL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7177927
发货至: 中国
  • 抗原 See all CTCFL 抗体
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    抗原表位
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-636
    适用
    • 28
    • 10
    • 3
    小鼠
    宿主
    • 30
    • 1
    • 1
    • 1
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTCFL antibody is un-conjugated
    应用范围
    • 27
    • 13
    • 13
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Mouse Transcriptional repressor CTCFL protein (1-636AA)
    亚型
    IgG
    Top Product
    Discover our top product CTCFL Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    别名
    Ctcfl (CTCFL 产品)
    别名
    BORIS antibody, CT27 antibody, CTCF-T antibody, HMGB1L1 antibody, dJ579F20.2 antibody, CTCFL antibody, Boris antibody, OTTMUSG00000016680 antibody, CCCTC-binding factor like antibody, CCCTC-binding factor (zinc finger protein)-like antibody, CTCFL antibody, Ctcfl antibody
    背景

    Background: Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 \\\'Arg-3\\\' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites. Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.

    Aliases: Ctcfl antibody, Boris antibody, Transcriptional repressor CTCFL antibody, Brother of the regulator of imprinted sites antibody, CCCTC-binding factor antibody, CTCF paralog antibody, CTCF-like protein antibody

    UniProt
    A2APF3
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