Perforin 1 抗体 (AA 21-554)
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- 抗原 See all Perforin 1 (PRF1) 抗体
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
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抗原表位
- AA 21-554
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Perforin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Mouse Perforin-1 protein (21-554AA)
- 亚型
- IgG
- Top Product
- Discover our top product PRF1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
- 别名
- Prf1 (PRF1 产品)
- 别名
- FLH2 antibody, HPLH2 antibody, P1 antibody, PFN1 antibody, PFP antibody, PRF1 antibody, Pfn antibody, Pfp antibody, Prf-1 antibody, Cyta antibody, RATCYTA antibody, LOC443187 antibody, perforin antibody, prf1 antibody, cytolysin antibody, perforin-1 antibody, perforin-1-like antibody, perforin 1 antibody, perforin 1 (pore forming protein) antibody, perforin antibody, perforin 1 L homeolog antibody, PRF1 antibody, Prf1 antibody, LOC443187 antibody, prf1 antibody, prf1.L antibody
- 背景
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Background: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
Aliases: Prf1 antibody, Pfp antibody, Perforin-1 antibody, P1 antibody, Cytolysin antibody, Lymphocyte pore-forming protein antibody
- UniProt
- P10820
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
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