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MAP2K4 抗体 (AA 2-397) (Biotin)

Name: MAP2K4 抗体 (AA 2-397) (Biotin)
Brand: antibodies-online
SKU: ABIN7177158
Availability: OutOfStock

MAP2K4 适用: 小鼠 ELISA 宿主: 兔 Polyclonal Biotin

产品编号 ABIN7177158

发货至: 中国

Datasheet as PDF

抗原 See all MAP2K4 抗体

MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
抗原表位
36

22

10

10

9

9

9

5

5

5

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2-397
适用
158

74

56

8

7

3

2

2

2

2

1

1

1
小鼠
宿主
150

12
兔
Compatible Secondaries
克隆类型
152

11
多克隆
标记
88

12

10

8

5

5

4

4

4

4

4

4

1

1

1

1

1

1

1

1

1

1

1
This MAP2K4 antibody is conjugated to Biotin
应用范围
89

71

64

26

22

15

15

13

6

6

3

3

2

2

2
ELISA

交叉反应

小鼠

纯化方法

>95%, Protein G purified

免疫原

Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 4 protein (2-397AA)

亚型

IgG

Top Product

Discover our top product MAP2K4 Primary Antibody
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IHC, IF, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 4B4 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 1D6 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E4 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 137-394) antibody
MAP2K4 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H4 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 1-399) antibody
MAP2K4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 259-398) antibody
MAP2K4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pSer80) antibody
MAP2K4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pThr261) antibody
MAP2K4 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

别名

Map2k4 (MAP2K4 产品)

别名

JNKK antibody, JNKK1 antibody, MAPKK4 antibody, MEK4 antibody, MKK4 antibody, PRKMK4 antibody, SAPKK-1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Sek1 antibody, Serk1 antibody, MKK4A-l antibody, map2k4 antibody, zgc:136500 antibody, jnkk antibody, mek4 antibody, mkk4 antibody, sek1 antibody, jnkk1 antibody, serk1 antibody, xmek2 antibody, mapkk4 antibody, prkmk4 antibody, 142758_at antibody, CG9738 antibody, CT27508 antibody, D-MKK4 antibody, DMKK4 antibody, Dmel\\CG9738 antibody, JNKK2 antibody, Mpk4 antibody, SEK1/MKK4 antibody, dMKK4 antibody, dMkk4 antibody, hep antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antibody, ATMEK4 antibody, ATMKK4 antibody, F19C24.26 antibody, F19C24_26 antibody, MAP KINASE KINASE 4 antibody, mitogen-activated protein kinase kinase 4 antibody, MKK4B antibody, zgc:194486 antibody, mitogen-activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4a antibody, MAP kinase kinase 4 antibody, mitogen activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4b antibody, MAP2K4 antibody, Map2k4 antibody, map2k4a antibody, map2k4 antibody, Mkk4 antibody, MKK4 antibody, map2k4b antibody

背景

Background: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The phosphorylation of the Thr residue by MAP2K7/MKK7 seems to be the prerequisite for JNK activation at least in response to proinflammatory cytokines, while other stimuli activate both MAP2K4/MKK4 and MAP2K7/MKK7 which synergistically phosphorylate JNKs. MAP2K4 is required for maintaining peripheral lymphoid homeostasis. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. Whereas MAP2K7/MKK7 exclusively activates JNKs, MAP2K4/MKK4 additionally activates the p38 MAPKs MAPK11, MAPK12, MAPK13 and MAPK14.
Aliases: Map2k4 antibody, Jnkk1 antibody, Mek4 antibody, Mkk4 antibody, Prkmk4 antibody, Sek1 antibody, Serk1 antibody, Skk1 antibody, Dual specificity mitogen-activated protein kinase kinase 4 antibody, MAP kinase kinase 4 antibody, MAPKK 4 antibody, EC 2.7.12.2 antibody, C-JUN N-terminal kinase kinase 1 antibody, JNK kinase 1 antibody, JNKK 1 antibody, JNK-activating kinase 1 antibody, MAPK/ERK kinase 4 antibody, MEK 4 antibody, SAPK/ERK kinase 1 antibody, SEK1 antibody

UniProt

P47809

途径

MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling