GLIS2 抗体 (AA 332-505) (Biotin)
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- 抗原 See all GLIS2 抗体
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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抗原表位
- AA 332-505
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLIS2 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Zinc finger protein GLIS2 protein (332-505AA)
- 亚型
- IgG
- Top Product
- Discover our top product GLIS2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
- 别名
- GLIS2 (GLIS2 产品)
- 别名
- glis2b antibody, nkl-A antibody, xNKLb antibody, NKL antibody, NPHP7 antibody, Gli5 antibody, Klf16 antibody, Nkl antibody, glis2a antibody, nphp7 antibody, GLIS family zinc finger 2 L homeolog antibody, GLIS family zinc finger 2 antibody, GLIS family zinc finger 2 S homeolog antibody, glis2.L antibody, GLIS2 antibody, Glis2 antibody, glis2.S antibody
- 背景
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Background: Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).
Aliases: FLJ38247 antibody, GLI similar 2 antibody, GLI-similar 2 antibody, GLIS 2 antibody, GLIS family zinc finger 2 antibody, glis2 antibody, GLIS2_HUMAN antibody, Kruppel like zinc finger protein GLIS2 antibody, Neuronal Krueppel-like protein antibody, Zinc finger protein GLIS2 antibody
- UniProt
- Q9BZE0
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