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WDR41 抗体 (AA 7-284) (FITC)

WDR41 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7175753
发货至: 中国
  • 抗原 See all WDR41 products
    WDR41 (WD Repeat Domain 41 (WDR41))
    抗原表位
    • 8
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 7-284
    适用
    • 32
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 27
    • 5
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WDR41 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human WD repeat-containing protein 41 protein (7-284AA)
    亚型
    IgG
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WDR41 (WD Repeat Domain 41 (WDR41))
    别名
    WDR41 (WDR41 产品)
    别名
    WDR41 antibody, MGC142930 antibody, wdr41 antibody, fj48d04 antibody, wu:fj48d04 antibody, zgc:110041 antibody, B830029I03Rik antibody, MSTP048 antibody, WD repeat domain 41 antibody, Wdr41 antibody, WDR41 antibody, wdr41 antibody
    背景

    Background: Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).

    Aliases: FLJ10904 antibody, MSTP048 antibody, WD repeat domain 41 antibody, WD repeat protein 41 antibody, WD repeat-containing protein 41 antibody, WDR 41 antibody, WDR41 antibody, WDR41_HUMAN antibody

    UniProt
    Q9HAD4
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