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WIPI1 抗体 (AA 187-446)

WIPI1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7175707
发货至: 中国
  • 抗原 See all WIPI1 抗体
    WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-446
    适用
    • 31
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    宿主
    • 28
    • 3
    克隆类型
    • 27
    • 4
    多克隆
    标记
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    This WIPI1 antibody is un-conjugated
    应用范围
    • 30
    • 18
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human WD repeat domain phosphoinositide-interacting protein 1 protein (187-446AA)
    亚型
    IgG
    Top Product
    Discover our top product WIPI1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WIPI1 (WD Repeat Domain, phosphoinositide Interacting 1 (WIPI1))
    别名
    WIPI1 (WIPI1 产品)
    别名
    ATG18 antibody, ATG18A antibody, WIPI49 antibody, 4930533H01Rik antibody, AW411817 antibody, D11Ertd498e antibody, RGD1307754 antibody, zgc:64205 antibody, WIPI1 antibody, atg18 antibody, wipi49 antibody, MGC145296 antibody, rgs9 antibody, wipi1 antibody, zgc:152760 antibody, WD repeat domain, phosphoinositide interacting 1 antibody, WD repeat domain, phosphoinositide interacting 1 S homeolog antibody, regulator of G protein signaling 9a antibody, WIPI1 antibody, Wipi1 antibody, wipi1 antibody, wipi1.S antibody, rgs9a antibody
    背景

    Background: Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway.

    Aliases: ATG 18 antibody, ATG18 antibody, Atg18 protein homolog antibody, ATG18A antibody, FLJ10055 antibody, WD repeat domain phosphoinositide interacting 1 antibody, WD repeat domain phosphoinositide interacting protein 1 antibody, WD repeat domain phosphoinositide-interacting protein 1 antibody, WD40 repeat protein interacting with phosphoinositides of 49 kDa antibody, WD40 repeat protein interacting with phosphoInositides of 49 kDa antibody, WIPI 1 alpha antibody, WIPI 1 antibody, WIPI 49 antibody, WIPI 49 kDa antibody, WIPI-1 antibody, wipi1 antibody, WIPI1_HUMAN antibody, WIPI49 antibody

    UniProt
    Q5MNZ9
    途径
    Nuclear Hormone Receptor Binding, ER-Nucleus Signaling
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