WDFY3 抗体 (AA 1-100)
-
- 抗原 See all WDFY3 抗体
- WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))
-
抗原表位
- AA 1-100
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This WDFY3 antibody is un-conjugated
-
应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human WD repeat and FYVE domain-containing protein 3 protein (1-100AA)
- 亚型
- IgG
- Top Product
- Discover our top product WDFY3 Primary Antibody
-
-
- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))
- 别名
- WDFY3 (WDFY3 产品)
- 别名
- ALFY antibody, ZFYVE25 antibody, 2610509D04Rik antibody, AW319683 antibody, B930017C24 antibody, BWF1 antibody, Bchs antibody, D5Ertd66e antibody, Ggtb3 antibody, mKIAA0993 antibody, WDFY family member 4 antibody, WD repeat and FYVE domain containing 3 antibody, WD repeat and FYVE domain-containing protein 3 antibody, WDFY4 antibody, WDFY3 antibody, MGYG_03998 antibody, Wdfy3 antibody
- 背景
-
Background: Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
Aliases: WDFY3 antibody, KIAA0993 antibody, WD repeat and FYVE domain-containing protein 3 antibody, Autophagy-linked FYVE protein antibody, Alfy antibody
- UniProt
- Q8IZQ1
-