VPS4A 抗体 (AA 1-120)
Quick Overview for VPS4A 抗体 (AA 1-120) (ABIN7175319)
抗原
See all VPS4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-120
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Vacuolar protein sorting-associated protein 4A protein (1-120AA)
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亚型
- IgG
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anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (N-Term) antibody
VPS4A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) antibodyVPS4A 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 44-77), (N-Term) antibodyVPS4A 适用: 人 WB 宿主: 兔 Polyclonal RB49739 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 1-437) antibodyVPS4A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 74-123) antibodyVPS4A 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 38-87) antibodyVPS4A 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 斑马鱼, Hamster, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
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别名
- VPS4A
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背景
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Background: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis: retained at the midbody by ZFYVE19/ANCHR and CHMP4C until abscission checkpoint signaling is terminated at late cytokinesis. It is then released following dephosphorylation of CHMP4C, leading to abscission (PubMed:24814515). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
Aliases: hVPS4 antibody, Protein SKD2 antibody, SKD1 antibody, SKD1 homolog antibody, SKD1A antibody, SKD2 antibody, Vacuolar protein sorting 4 homolog A antibody, Vacuolar protein sorting 4, yeast, homolog of, A antibody, Vacuolar protein sorting factor 4A antibody, Vacuolar protein sorting-associated protein 4A antibody, vacuolar sorting protein 4 antibody, VPS4 antibody, VPS4-1 antibody, Vps4a antibody, VPS4A_HUMAN antibody
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UniProt
- Q9UN37
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途径
- Microtubule Dynamics, CXCR4-mediated Signaling Events
抗原
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